OXA-1 β-lactamase and non-susceptibility to penicillin/β-lactamase inhibitor combinations among ESBL-producingEscherichia coli
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چکیده
منابع مشابه
Detection of Plasmid-Borne β-Lactamase Genes in Extended- Spectrum β-Lactamase (ESBL) and Non-ESBL-Producing Escherichia coli Clinical Isolates
Increasing frequency of infections caused by antibiotic resistant Escherichia coli strains producing extended-spectrum β-lactamase (ESBL) needs to be addressed by continuous surveillance and accurate detection of specific ESBLs genes for more effective treatment. A total of 71 β-lactam drug resistant isolates (26 phenotypically ESBL-producing and 45 non-ESBLproducing) were observed to carry app...
متن کاملAntimicrobial Susceptibility Profile of Extended Spectrum β-Lactamase (ESBL) Producing Escherichia coli from Various Clinical Samples
BACKGROUND Extended spectrum β-lactamase (ESBL) producing Escherichia coli has tremendously increased worldwide and it is one of the most common causes of morbidity and mortality associated with hospital-acquired infections. This could be attributed to association of multi drug resistance in ESBL producing isolates. The present study was aimed to determine the antimicrobial sensitivity profile ...
متن کاملCombinatorial Pharmacodynamics of Ceftolozane-Tazobactam against Genotypically Defined β-Lactamase-Producing Escherichia coli: Insights into the Pharmacokinetics/Pharmacodynamics of β-Lactam-β-Lactamase Inhibitor Combinations.
Despite a dearth of new agents currently being developed to combat multidrug-resistant Gram-negative pathogens, the combination of ceftolozane and tazobactam was recently approved by the Food and Drug Administration to treat complicated intra-abdominal and urinary tract infections. To characterize the activity of the combination product, time-kill studies were conducted against 4 strains ofEsch...
متن کاملPrevalence of extended spectrum β-lactamase (ESBL) producing E. coli and Klebsiella species in urinary isolates
Introduction: Bacterial resistance to β-lactam antibiotics has risen dramatically, with extended spectrum βlactamase (ESBL) contributing to this increase. Early identification of ESBL production is becoming increasingly important. Methodology: A total of 367 consecutive, urine samples from patients suspected to have UTI, were processed. All Escherichia coli and Klebsiella species isolated in si...
متن کاملPrevalence and antimicrobial susceptibility patterns of ESBL, AmpC and Carbapenemase- producing Enterobactericeae isolated from hospitalized patients in Azerbaijan, Iran
Current study was conducted to determine prevalence and antimicrobial susceptibility patterns, ESBL, AmpC and carbapenemase- producers among clinical isolates of Enterobacteriaceae. Three hundred and seven non-duplicative clinical isolates were collected from hospitalized patients in five medical centers in Azerbaijan, Iran. Initial screening for β-lactamase production was performed using disc ...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2018
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/dky453